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EPSRC Support by Research Area (Synthetic Organic Chemistry) in Theme (Physical Sciences)

Research areas are used to describe EPSRC's portfolio of excellent long term research and high quality postgraduate training.

Grants are classified using one or more research areas. The number and value of grants listed below reflects how the theme portfolio is described by this research area.

Please note: some research areas will appear under multiple themes. There is no unique, absolute, relationship between a research area and a theme.

Grant TitlePrincipal
Investigator		OrganisationDepartmentTotal Grant
Value (£)
18F-Difluoromethylation: The Missing Link in Radiochemistry for Positron Emission TomographyGouverneur, Professor VUniversity of OxfordOxford Chemistry 506,886
3DSynth: Design and fabrication of cartridges for digital chemical synthesisCronin, Professor LUniversity of GlasgowSchool of Chemistry 999,034
A Fully-Automated Robotic System For Intelligent Chemical Reaction ScreeningFairlamb, Professor IJUniversity of YorkChemistry 201,478
A Multi-Component Strategy for the Synthesis of Complex Aliphatic Amines using Photo-redox CatalysisGaunt, Professor MUniversity of CambridgeChemistry 703,740
A New Class of Hybrid Polyoxometalate Catalysts for C-H FunctionalisationLam, Professor HWUniversity of NottinghamSch of Chemistry 201,902
A Protein Functionalization Platform Based on Selective Modification at Methionine ResiduesGaunt, Professor MUniversity of CambridgeChemistry 1,892,760
A Radical Amination Approach to Aliphatic AminesCuthbertson, Dr JUniversity of NottinghamSch of Chemistry 406,784
A Radical Approach to C-H AlkylationCresswell, Dr AJUniversity of BathChemistry 261,307
AA-STARR: Aromatic Amine Synthesis by Tapping Aminium Radical ReactivityMarsden, Professor SPUniversity of LeedsSch of Chemistry 402,890
Accessing pharmacophoric space via asymmetric protonationWatson, Dr AJBUniversity of St AndrewsChemistry 399,956
An Artificial RibosomeO'Reilly, Professor RKUniversity of BirminghamSchool of Chemistry 581,943
An Artificial RibosomeTurberfield, Professor AJUniversity of OxfordOxford Physics 664,201
An EPSRC National Research Facility to facilitate Data Science in the Physical Sciences: The Physical Sciences Data science Service (PSDS)Coles, Professor SJUniversity of SouthamptonSch of Chemistry 2,996,067
Anti tumour agents from natural products - new approaches to targeting ultra potent analogues of the duocarmycinsSearcey, Professor MUniversity of East AngliaPharmacy 450,207
Application by the School of Chemistry and the School of Pharmacy, University of East Anglia, for enhanced single-crystal X-ray diffraction facilitiesBochmann, Professor MUniversity of East AngliaChemistry 616,064
Artificial and Augmented Intelligence for Automated Scientific DiscoveryFrey, Professor JGUniversity of SouthamptonSch of Chemistry 1,014,318
Artificial photosynthesis strategies for synthesis: Combined photoredox and transition metal-catalysed transfer hydrogenation of C-C multiple bondsCambeiro, Dr XCUniversity of GreenwichPharm., Chem. & Environmental Sci., FES 202,477
Atomic and Molecular Endofullerenes: Spins in a boxLevitt, Professor MHUniversity of SouthamptonSch of Chemistry 1,179,731
Automating the Synthetic Chemistry Landscape in Bristol: Accelerating Impact and ApplicationAggarwal, Professor VKUniversity of BristolChemistry 766,927
Autonomous Discovery of Functional Small MoleculesNelson, Professor ASUniversity of LeedsSch of Chemistry 1,245,808
Bespoke Bimetallics for Chemical CooperativityMulvey, Professor RUniversity of StrathclydePure and Applied Chemistry 569,181
Boronic Acid-Catalysed Dehydrative SynthesisTaylor, Dr JEUniversity of BathChemistry 314,716
Cast iron catalysis: New catalytic protocols for carbon-phosphorus bond synthesisWebster, Dr RUniversity of BathChemistry 1,062,652
Catalysing 3 routes to C-H Borylation using Earth-abundant MetalsIngleson, Professor MJUniversity of EdinburghSch of Chemistry 510,419
Centre for Rapid Online Analysis of Reactions (ROAR), Phase IIHii, Professor KK(Imperial College LondonChemistry 231,296
C-H functionalisation of saturated nitrogen heterocycles, building blocks for drug discoveryColdham, Professor IUniversity of SheffieldChemistry 348,643
Chemistry of open-shell correlated materials based on unsaturated hydrocarbonsRosseinsky, Professor MUniversity of LiverpoolChemistry 763,195
Chemobots: Digital-Chemical-Robotics to Convert Code to Molecules and Complex SystemsCronin, Professor LUniversity of GlasgowSchool of Chemistry 5,034,017
Chemoselective cross-coupling via control of anion metathesis at Pd(II)Watson, Dr AJBUniversity of St AndrewsChemistry 384,880
Complex made simple: Enantioselective radical cascades mediated by SmI2Kaltsoyannis, Professor NUniversity of Manchester, TheChemistry 543,719
Construction of 18F-perfluorinated motifs by mechanistic leverage with fluorineTredwell, Dr MCardiff UniversitySchool of Medicine 392,297
Convergent Bidirectional Total Synthesis of Ciguatoxin CTX3CClark, Professor JUniversity of GlasgowSchool of Chemistry 724,061
CRISPR ChemistryBrown, Professor TUniversity of OxfordOxford Chemistry 254,184
Cu-Catalysed Amination of Alkylboronic EstersPartridge, Dr BMUniversity of SheffieldChemistry 312,477
Developing Continuous Electroorganic Catalysis - It's Got PotentialMorrill, Dr L CCardiff UniversityChemistry 395,968
Development of a generally applicable catalytic amidation reactionWhiting, Professor ADurham, University ofChemistry 24,409
Development of a generally applicable catalytic direct amidation reactionBures, Dr JUniversity of Manchester, TheChemistry 285,613
Development of a generally applicable catalytic direct amidation reactionRzepa, Professor HSImperial College LondonChemistry 270,130
Development of a generally applicable catalytic direct amidation reactionSheppard, Professor TDUCLChemistry 336,290
Dual Unsaturated Transition Metal-Main Group (TM-M') Heterobimetallic Complexes for Cooperative Reactivity and CatalysisMacgregor, Professor SAHeriot-Watt UniversitySch of Engineering and Physical Science 349,787
Dual Unsaturated Transition Metal-Main Group (TM-M') Heterobimetallic Complexes for Cooperative Reactivity and CatalysisWhittlesey, Professor MUniversity of BathChemistry 427,065
Dynamic Resolution of Boronic Esters: A Powerful Strategy for Asymmetric Atropisomer SynthesisHarrity, Professor JPAUniversity of SheffieldChemistry 377,889
Enabling industrial deployment of deep eutectic solvents through manufacturing toolsTorrente Murciano, Dr LUniversity of CambridgeChemical Engineering and Biotechnology 465,240
Enabling industrial deployment of deep eutectic solvents through manufacturing toolsHevia, Professor EUniversity of BernDept for Chemistry and Biochemistry 154,867
Enabling industrial deployment of deep eutectic solvents through manufacturing toolsEdler, Professor KUniversity of BathChemistry 387,156
Enantioconvergent Multi-Component Reactions.Lawrence, Professor ALUniversity of EdinburghSch of Chemistry 202,196
Enantioselective C-H C-H Coupling of Alcohols with HeteroarenesPhipps, Dr RJUniversity of CambridgeChemistry 355,413
EPSRC-SFI: Glycoconjugate tools for sensing endoglycosidase activity: a diagnostic sugar probe for heparanaseMiller, Dr GJKeele UniversityFaculty of Natural Sciences 368,582
Exploiting Chalcogen Bonding and Non-Covalent Interactions in Isochalcogenourea Catalysis: Catalyst Preparation, Mechanistic Studies and ApplicationsSmith, Professor ADUniversity of St AndrewsChemistry 736,798
Exploiting the interface between aromaticity and non-aromaticityDonohoe, Professor TUniversity of OxfordOxford Chemistry 390,108
FUNCTION THROUGH CHIRALITY IN ORGANIC ELECTRONIC MATERIALS AND DEVICESFuchter, Professor MJImperial College LondonChemistry 1,584,212
Functional Hydrogen-Bonded Self-Sorting NetworksWilson, Professor AJUniversity of LeedsSch of Chemistry 454,259
Growing Carbon Chains on Organometallic NetworksCrimmin, Dr MRImperial College LondonChemistry 423,568
High Intensity High Sensitivity X-ray DiffactionSchroder, Professor MUniversity of Manchester, TheChemistry 1,078,365
In-situ NMR-based methodology for screening and optimisation of heterogenised organocatalytic systemsD'Agostino, Dr CUniversity of Manchester, TheChem Eng and Analytical Science 187,839
Iron-Catalysed Oxygenation with O2Xiao, Professor JUniversity of LiverpoolChemistry 349,398
Light-Driven Multicomponent C-C Couplings: New Avenues to Bioactive MoleculesSilvi, Dr MUniversity of NottinghamSch of Chemistry 403,633
Merging Photoredox with 1,2-Boronate Rearrangements: New Opportunities for Rapid Increase in Molecular ComplexityAggarwal, Professor VKUniversity of BristolChemistry 705,116
Metal-organic nanosheets: a programmable two-dimensional platform for multistep catalysisFoster, Dr JAUniversity of SheffieldChemistry 385,936
Modify-catch-release-repeat: Reversible bioconjugations for controlled release of small molecules from antibodies and their fragmentsFascione, Dr M AUniversity of YorkChemistry 397,840
Modular approach to structurally diverse four-membered (spiro)cycles using highly strained precursorsAggarwal, Professor VKUniversity of BristolChemistry 581,589
Molecular assembly of spintronic circuits with DNAArdavan, Professor AUniversity of OxfordOxford Physics 1,772,989
Multi-inlet comprehensive gas chromatography and high resolution mass spectrometryLangley, Professor GJUniversity of SouthamptonSch of Chemistry 856,023
Nanostar Sieving for Oligonucleotides Manufacture (NanoSieveOligo)Livingston, Professor AImperial College LondonChemical Engineering 562,145
New Directions in Bioisostere ResearchAnderson, Professor EAUniversity of OxfordOxford Chemistry 572,768
NEW DIRECTIONS IN FLOW ELECTROSYNTHESISWirth, Professor TCardiff UniversityChemistry 468,778
New Reagents for Protein ModificationBaud, Dr MUniversity of SouthamptonSch of Chemistry 195,281
New sulfur-based reactive intermediates for synthesis and catalysisWillis, Professor MUniversity of OxfordOxford Chemistry 370,518
Next generation molecular imaging and therapy with radionuclidesBlower, Professor PKings College LondonImaging & Biomedical Engineering 6,437,106
NEXT GENERATION RUTHENIUM-CATALYSTS FOR LATE STAGE C-H FUNCTIONALISATIONLarrosa, Professor IUniversity of Manchester, TheChemistry 479,276
Nitrogen- and Oxygen-Radicals-Based Strategies for the Divergent Assembly of Novel Building Blocks by Strain-ReleaseLeonori, Professor DUniversity of Manchester, TheChemistry 391,803
Novel Strategies for the Assembly of Carbon-Boron Bonds via the Photoinduced Generation of Boryl-RadicalsLeonori, Professor DUniversity of Manchester, TheChemistry 375,981
Nucleophilic Alkaline Earth Boryls: From Conception and Theory to ApplicationHill, Professor MSUniversity of BathChemistry 1,277,229
Organocatalytic Mitsunobu Activation for Streamlined Pharmaceutical SynthesisDenton, Professor RMUniversity of NottinghamSch of Chemistry 398,593
Oscillating Photostationary States for Molecular Cargo TransportCollins, Dr BUniversity of BristolChemistry 201,845
Partially fluorinated alkyl motifs for pharmaceuticals and agrochemicals researchO'Hagan, Professor DUniversity of St AndrewsChemistry 424,425
Photo-Electro: Transforming Chemical Synthesis, Discovery and ManufactureGeorge, Professor MUniversity of NottinghamSch of Chemistry 6,486,390
Properties and applications of Janus faced fluorocyclohexanesO'Hagan, Professor DUniversity of St AndrewsChemistry 482,983
Property-Enhanced PorphyrinsChauvet, Dr A A PUniversity of SheffieldChemistry 379,306
Rapid Online Analysis of Reactions (ROAR)Hii, Professor KK(Imperial College LondonChemistry 2,757,688
Reactors and Reproducibility: Advancing Electrochemistry for Organic SynthesisLennox, Dr AJJUniversity of BristolChemistry 372,708
Site-selective functionalisation of peptides and proteins via free-radical-induced dechalcogenationMitchell, Dr NJUniversity of NottinghamSch of Chemistry 428,349
Spiroclip Technology: from Catalogue to Spirocycle in One StepUnsworth, Dr WPUniversity of YorkChemistry 367,413
Stereospecific Csp3-Csp2 Cross-Coupling of Saturated Heterocyclic Boronates: A Transformative Disconnection for Drug DiscoveryO'Brien, Professor PUniversity of YorkChemistry 202,415
Sulfoxides as substrate activators: New cross-couplings for making materials and medicinesProcter, Professor DJUniversity of Manchester, TheChemistry 730,401
Synthesis and Structure Elucidation of Natural ProductsAggarwal, Professor VKUniversity of BristolChemistry 1,526,094
Tiger in a Cage: Detecting Single Photons at low GHz Frequencies without Refrigerators, Vacuum Chambers or MagnetsOxborrow, Dr MImperial College LondonMaterials 202,255
Underpinning Mechanistic Studies of NHC-Organocatalysis: A Breslow Intermediate Reactivity ScaleSmith, Professor ADUniversity of St AndrewsChemistry 398,308
Underpinning Mechanistic Studies of NHC-Organocatalysis: A Breslow Intermediate Reactivity ScaleO'Donoghue, Professor ACDurham, University ofChemistry 435,967

Total Number of Grants: 89
Total Value of Grants: £68,774,519

The grant value may include the cost of access to facilities (these funds are not awarded to the grant holding organisation).