| EPSRC Reference: |
DT/E010792/1 |
| Title: |
SeaScreen: expanding a bioprocess repertoire by smart marine microbe screening. |
| Principal Investigator: |
Keane, Professor MA |
| Other Investigators: |
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| Researcher Co-Investigators: |
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| Project Partners: |
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| Department: |
Sch of Engineering and Physical Science |
| Organisation: |
Heriot-Watt University |
| Scheme: |
Technology Programme |
| Starts: |
01 March 2007 |
Ends: |
31 August 2010 |
Value (£): |
128,947
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| EPSRC Research Topic Classifications: |
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| EPSRC Industrial Sector Classifications: |
| Pharmaceuticals and Biotechnology |
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| Panel History: |
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Summary on Grant Application Form |
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The aim of this proposal is to discover new oxidase enzymes with industrially relevant substrate specificities for integration with the Ingenza deracemisation bioprocess for the manufacture of enantiopure chiral amines and amino acids. Currently, the technology cannot be used on the majority of substrates in the (R)-amine or L-amino acid families due to the lack of suitable oxidases and significant markets are therefore inaccessible. Marine microorganisms represent a vast, diverse and underdeveloped source of novel enzymes for biocatalysis. This project brings together significant members of the fields of marine biotechnology and biocatlaysis for the first time and will deliver industrially useful novel oxidases by developing highly innovative and powerful screening and selection technologies and novel, high yielding, scalable and economic enzyme production systems.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.hw.ac.uk |