| EPSRC Reference: |
EP/C004922/1 |
| Title: |
Ink Jet Printing and Co-Seeding of 2- and 3-Dimensional Cell Arrays |
| Principal Investigator: |
Derby, Professor B |
| Other Investigators: |
|
| Researcher Co-Investigators: |
|
| Project Partners: |
|
| Department: |
Materials |
| Organisation: |
University of Manchester, The |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
01 May 2005 |
Ends: |
31 October 2006 |
Value (£): |
96,428
|
| EPSRC Research Topic Classifications: |
|
| EPSRC Industrial Sector Classifications: |
|
| Related Grants: |
|
| Panel History: |
|
|
Summary on Grant Application Form |
|
This proposal is a feasibility study for the use of ink jet printing as a tool to fabricate structures that contain living cells. These structures can be precisely designed to provide a local microenvironment through which the cells function can be monitored, controlled and possibly induced. To achieve this we will develop novel materials and processes, combining ink jet printing with photo-polymerisation, that allow us to control the microstructure through printing and the nanostructure through appropriate materials design. Previous study has demostrated that we can deliver cells by ink-jet printing and so co-seeded structures will be produced during manufacture.Preliminary work will construct simple 2D patterns. They will have sufficient vertical thickness to confine and isolate cells to allow the demonstration of the technique and easy access for optical methods to study cells and cell populations. These constructs can be used to study intercellular communication by careful design of the local environment.If successful, a subsequent flagship project would extend the method to 3D constructs enabling microbioreactors and seeded scaffolds for tissue engineering applications.
|
|
Key Findings |
|
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
|
|
Potential use in non-academic contexts |
|
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
|
|
Impacts |
|
| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
|
| Date Materialised |
|
|
|
|
Sectors submitted by the Researcher |
|
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
|
| Project URL: |
|
| Further Information: |
|
| Organisation Website: |
http://www.man.ac.uk |