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Details of Grant 

EPSRC Reference: EP/C512618/1
Title: Electromechanically Driven Surface Microfluidics On A Micro-Chip
Principal Investigator: Morgan, Professor H
Other Investigators:
Green, Dr NG
Researcher Co-Investigators:
Project Partners:
Department: Electronics and Computer Science
Organisation: University of Southampton
Scheme: Standard Research (Pre-FEC)
Starts: 18 April 2005 Ends: 17 October 2006 Value (£): 34,952
EPSRC Research Topic Classifications:
Microsystems
EPSRC Industrial Sector Classifications:
Chemicals Pharmaceuticals and Biotechnology
Related Grants:
Panel History:  
Summary on Grant Application Form
The convergence of several different micro-technologies has led to great advances in field of micro-total analysis and Lab-on-a-chip systems. For fully automated function of these complex systems, a microfluidic subsystem is needed to transport, manipulate and dispense sub-microlitre quantities of liquid containing chemical or biochemical material. This has traditionally been achieved using electroosmosis and/or electrophoresis to move particles and liquids through closed microchannels etched in glass, silicon, or polymer materials. However, each of these methods has drawbacks. A new approach to microfluidics has recently been developed. This relies on moving and manipulating very small liquid droplets on the surface of a microchip using electric fields. The chip is patterned with arrays of interdigitated electrodes and the droplets are individually manipulated using a programmable electronic chip-platform. The droplets carry the cells or reagents necessary for performing chemical and biochemical reactions on the chip. Droplet transport is important, but other operating capabilities including dispensing, metering, and mixing are also essential to a microfluidic system. Many promising (bio)chemical probes for molecular detection as well as cell-sorting, separation, and interrogation techniques have been demonstrated in the laboratory. However, to implement these schemes within an bio-chip system, integration at tine chip level with a microfluidic sub-systems is crucial. This programme will provide proof-of-concept forthis.
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Organisation Website: http://www.soton.ac.uk