| EPSRC Reference: |
EP/C531280/1 |
| Title: |
A Truly Global Virtual Research Environment for the Modelling & Simulation of the Heart |
| Principal Investigator: |
Gavaghan, Professor D |
| Other Investigators: |
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| Project Partners: |
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| Department: |
Computer Science |
| Organisation: |
University of Oxford |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
05 July 2005 |
Ends: |
04 January 2008 |
Value (£): |
41,200
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| EPSRC Research Topic Classifications: |
| Mathematical Analysis |
Software Engineering |
| Theoretical biology |
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| Panel History: |
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Summary on Grant Application Form |
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The primary aim of the Integrative Biology project is the development of the Computational Infrastructure using state of the art technologies (termed Grid Middleware ) required to support post-genomic research in biology and medicine. Integrative or systems approaches to research in biology are evolving very rapidly, driven by a pressing need to understand how the components that make up a biological system interact to allow biological function, such as the beating of the human heart, to emerge, and to express that understanding in quantitative (i.e. mathematical) terms. It is now widely accepted that this can only be achieved by close collaboration between experimentalists, mathematicians, and computer scientists.The IB consortium initially represented a collaboration between 6 leading UK Universities (Oxford, Nottingham, Leeds, UCL, Birmingham and Sheffield), the Bioengineering Institute at the University of Auckland, the Central Laboratories of the Research Councils and the IBM corporation. To test fully the computational or Grid infrastructure that we intend to develop, we are now requesting funding through this proposal to extend the consortium to include three leading heart-modelling groups in the USA led by Professors Natalia Trayanova at Tulane, Andrew McCulloch at UCSD, and Alan Garfinkel at UCLA. This will be achieved through a series of annual visits by UK researchers to the US to install middleware and to train users, and an annual workshop in the UK at which researchers from the US will report on their experiences of using the system and suggest improvements. The final deliverable of the project will be a truly global computational grid infrastructure supporting the research of a leading international research community.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.ox.ac.uk |