| EPSRC Reference: |
EP/C531922/1 |
| Title: |
Novel Chiral N-Heterocyclic Carbenes as Ligands for Metal-Mediated Asymmetric Processes |
| Principal Investigator: |
Lindsay, Dr DM |
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| Department: |
Chemistry |
| Organisation: |
University of Bristol |
| Scheme: |
First Grant Scheme Pre-FEC |
| Starts: |
01 October 2005 |
Ends: |
31 December 2008 |
Value (£): |
110,291
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Summary on Grant Application Form |
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Asymmetric metal-mediated processes are vital in organic synthesis. For many years, chiral phosphines have provided the source of asymmetry chiral metal complexes. In recent years, however, N-heterocyclic carbenes (NHCs) have begun to play a prominent role as ligands in many metal mediated processes, to the textent that they now rival, and often surpass, phosphines in this role. However, in the more specialised field of asymi catalysis, NHCs still lag behind phosphines. The research described herein is directed towards the preparation of new chiral NHC metal complex their application is asymmetric synthesis, and in particular, in asymmetric alkene metathesis processes. It is also important to recognise that NH( form complexes with main group metals and non-metals, and that these complexes may also be useful in synthesis. This area is so far unexplore this research project will investigate the potential of NHC main group complexes in organic synthesis.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.bris.ac.uk |