| EPSRC Reference: |
EP/C549406/1 |
| Title: |
Agent-Based and Continuum Modelling of Populations of Cells |
| Principal Investigator: |
Logan, Dr B |
| Other Investigators: |
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| Project Partners: |
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| Department: |
School of Computer Science |
| Organisation: |
University of Nottingham |
| Scheme: |
Discipline Hopping Pre-FEC |
| Starts: |
26 September 2005 |
Ends: |
25 September 2006 |
Value (£): |
38,682
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| EPSRC Research Topic Classifications: |
| Continuum Mechanics |
Fundamentals of Computing |
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| EPSRC Industrial Sector Classifications: |
| No relevance to Underpinning Sectors |
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| Panel History: |
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Summary on Grant Application Form |
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Many biological problems involve a wide range of scales, from, say, an individual gene operating within a cell to a very large population of cells operating in concert. While the latter aspect is widely recognised in the context of distinct organs within the human body, for example, its significance in bacterial populations (associated with a phenomenon known as 'quorum sensing') has been appreciated only relatively recently. These advances, together with the increasing medical challenges arising from the development among bacteria of resistance to the available antibiotics, motivates efforts to understand such processes through the development of suitable mathematical models. These models should encompass the complex behaviour that occurs both within a single cell and at the level of the whole population of cells; to bridge these scales it is highly desirable that the models be able to incorporate very large numbers of cells, each of which has significant internal structure. The current project seeks to develop such models by combining the distinct skills of a computer scientist and a mathematical modeller in such a way that these challenges can be addressed.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.nottingham.ac.uk |