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Details of Grant 

EPSRC Reference: EP/D001994/1
Title: Delayed Fluorescence as a New Form of Molecular Imaging
Principal Investigator: Harriman, Professor A
Other Investigators:
Benniston, Professor A
Researcher Co-Investigators:
Project Partners:
Department: School of Chemistry
Organisation: Newcastle University
Scheme: Standard Research (Pre-FEC)
Starts: 01 September 2005 Ends: 31 August 2006 Value (£): 85,402
EPSRC Research Topic Classifications:
Chemical Biology Lasers & Optics
EPSRC Industrial Sector Classifications:
Healthcare
Related Grants:
Panel History:  
Summary on Grant Application Form
There is extensive current interest in the design of selective reagents that permit the detection and treatment of a broad spectrum of biological processes, disorders and diseases and across organ systems. Typical biomedical imaging protocols involve fluorescence, ultrasound, NMR or radiolabels and make heavy use of modern computer technology to provide real-time images. We intend to develop an additional form of biomedical imaging that allows facile recognition of selective targets by way of delayed fluorescence. This protocol will combine the high sensitivity of fluorescence spectroscopy with the temporal and spatial resolution of gated optical microscopy. The unique aspect of our work is that a signal is detected only in the presence of a target of a particular size and shape. Here, we seek to examine the feasibility of applying the technique of triplet-triplet annihilation to support imaging and engineering research with potential medical applications.
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Organisation Website: http://www.ncl.ac.uk