EPSRC Reference: |
EP/D003849/1 |
Title: |
Three Dimensional Cell Addressing: A Proof-of-Concept Study in the Formation of Complex Tissue Architectures In Vitro |
Principal Investigator: |
Shakesheff, Professor K |
Other Investigators: |
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Researcher Co-Investigators: |
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Project Partners: |
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Department: |
Sch of Pharmacy |
Organisation: |
University of Nottingham |
Scheme: |
Standard Research (Pre-FEC) |
Starts: |
03 October 2005 |
Ends: |
02 February 2007 |
Value (£): |
87,989
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EPSRC Research Topic Classifications: |
Medical science & disease |
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EPSRC Industrial Sector Classifications: |
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Related Grants: |
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Panel History: |
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Summary on Grant Application Form |
A remarkable feature of human tissues is the precise architectural arrangement of cells. Within a single tissue, multiple cell types are arranged on the micron scale to form interconnected communities and on the 10 micron to 10 centimeter scale to form complex shapes. This three-dimensional architecture is vital to define the ultimate cell phenotype and tissue function. This proposal details a new basic technology that we believe can enable researchers to precisely position multiple cell types in vitro within a 3D space. This technology could bridge the gap between the elegance of self-assembly during in vivo organogenesis and the simple methods of assembling 3D tissue cultures used in the laboratory.
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Key Findings |
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Potential use in non-academic contexts |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
Summary |
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Date Materialised |
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Sectors submitted by the Researcher |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Project URL: |
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Further Information: |
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Organisation Website: |
http://www.nottingham.ac.uk |