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Details of Grant 

EPSRC Reference: EP/D003849/1
Title: Three Dimensional Cell Addressing: A Proof-of-Concept Study in the Formation of Complex Tissue Architectures In Vitro
Principal Investigator: Shakesheff, Professor K
Other Investigators:
Thomas, Professor D Crowe, Professor J Rose, Professor FRA
Researcher Co-Investigators:
Project Partners:
Department: Sch of Pharmacy
Organisation: University of Nottingham
Scheme: Standard Research (Pre-FEC)
Starts: 03 October 2005 Ends: 02 February 2007 Value (£): 87,989
EPSRC Research Topic Classifications:
Medical science & disease
EPSRC Industrial Sector Classifications:
Healthcare
Related Grants:
Panel History:  
Summary on Grant Application Form
A remarkable feature of human tissues is the precise architectural arrangement of cells. Within a single tissue, multiple cell types are arranged on the micron scale to form interconnected communities and on the 10 micron to 10 centimeter scale to form complex shapes. This three-dimensional architecture is vital to define the ultimate cell phenotype and tissue function. This proposal details a new basic technology that we believe can enable researchers to precisely position multiple cell types in vitro within a 3D space. This technology could bridge the gap between the elegance of self-assembly during in vivo organogenesis and the simple methods of assembling 3D tissue cultures used in the laboratory.
Key Findings
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Summary
Date Materialised
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Further Information:  
Organisation Website: http://www.nottingham.ac.uk