| EPSRC Reference: |
EP/H00727X/1 |
| Title: |
Micro-channel electrode neural interfaces: restoring bladder control |
| Principal Investigator: |
Fawcett, Professor J |
| Other Investigators: |
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| Researcher Co-Investigators: |
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| Project Partners: |
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| Department: |
Cambridge Centre for Brain Repair |
| Organisation: |
University of Cambridge |
| Scheme: |
Standard Research |
| Starts: |
01 October 2009 |
Ends: |
30 June 2013 |
Value (£): |
1,055,228
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| EPSRC Research Topic Classifications: |
| Med.Instrument.Device& Equip. |
Tissue Engineering |
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| EPSRC Industrial Sector Classifications: |
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| Related Grants: |
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| Panel History: |
| Panel Date | Panel Name | Outcome |
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09 Jun 2009
|
Basic Technology Translation Grants Call 4
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Announced
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Summary on Grant Application Form |
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In the Basic Technology project, we have developed a novel design of peripheral nerve interface. By placing axons into polymeric micro-channels hosting embedded electrodes the extracelluar amplitude of action potentials is greatly increased, allowing for robust recording, noise suppression and efficient stimulation. In the Translational project, we plan to implement our concept to restore bladder control first in an experimental rat model, and then in a clinical therapeutic veterinary model. The electrode interfaces will be implanted to record electrical activity from afferents, including those that encode bladder fullness and pressure. Non regenerative then regenerative nerve interfaces with their communication system will be fabricated and tested to treat incontinent dogs suffering from spinal cord injury. Results from our study will provide a direct pathway for treating the equivalent condition in human patients.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
http://www.brc.cam.ac.uk |
| Further Information: |
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| Organisation Website: |
http://www.cam.ac.uk |