| EPSRC Reference: |
EP/H04986X/1 |
| Title: |
Engineering a semi-biotic immune system |
| Principal Investigator: |
Tavassoli, Professor A |
| Other Investigators: |
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| Researcher Co-Investigators: |
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| Project Partners: |
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| Department: |
Sch of Chemistry |
| Organisation: |
University of Southampton |
| Scheme: |
Standard Research |
| Starts: |
01 August 2010 |
Ends: |
31 January 2016 |
Value (£): |
1,031,745
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| EPSRC Research Topic Classifications: |
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| EPSRC Industrial Sector Classifications: |
| Healthcare |
Pharmaceuticals and Biotechnology |
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| Related Grants: |
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| Panel History: |
| Panel Date | Panel Name | Outcome |
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12 Feb 2010
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Engineering Challenges in Synthetic Biology
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Announced
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Summary on Grant Application Form |
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Synthetic biology is an emerging field that aims to engineer biological systems by utilising engineering principles, analytical technologies and increasing understanding from biological research. Some of the successes in this young field include bacterial production of the anti-malaria drug artemisinin and generation of significant private funding for basic research. We wish to move developments in Synthetic Biology from simple components towards integrated systems with higher functionalities. Specifically, our long-term goal is to design and fabricate a semi-biotic immune device. At its core, the device will use a consortium of engineered bacteria, composed of a group of detectors that monitor the host for signals of disease onset and responders, that await signals from the detecting bacteria, before initiating the production and release of the relevant small molecule treatment. The engineered bacteria will be interfaced with traditional electronic components that oversee, record and transmit the status of the unit. We envisage that this device will enable individual-specific, rapid and autonomic therapeutic intervention at the early stages of disease.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.soton.ac.uk |