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Details of Grant 

EPSRC Reference: EP/I036281/1
Title: Asymmetric Cross-Coupling via Iron-Catalysed Reductive Cross-Coupling
Principal Investigator: Thomas, Dr SP
Other Investigators:
Researcher Co-Investigators:
Project Partners:
Department: Chemistry
Organisation: University of Bristol
Scheme: First Grant - Revised 2009
Starts: 09 January 2012 Ends: 08 January 2013 Value (£): 99,842
EPSRC Research Topic Classifications:
Catalysis & Applied Catalysis Chemical Synthetic Methodology
EPSRC Industrial Sector Classifications:
No relevance to Underpinning Sectors
Related Grants:
Panel History:
Panel DatePanel NameOutcome
12 May 2011 EPSRC Physical Sciences Chemistry* Announced
Summary on Grant Application Form
The construction of complex molecular frameworks underpins the future development of everything from new medicines to novel materials. The ability to make carbon-carbon bonds is key to this development. A number of the most used methods to carry out this bond forming reaction rely on the use of expensive, toxic and environmentally damaging transition-metal catalysts.

This research programme aims to develop iron-based alternatives to the currently used methods and expand upon the scope and applicability of the current transformations. Iron catalysts offer the advantage of being inexpensive, non-toxic and environmentally benign and so are of great interest to the chemical community. Specifically, we will introduce a new carbon-carbon bond forming reaction with a concurrent reduction to produce fully saturated products (alkanes).

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Organisation Website: http://www.bris.ac.uk