EPSRC Reference: |
EP/J007145/1 |
Title: |
Towards excited state dynamics in nucleosides |
Principal Investigator: |
Stavros, Professor V |
Other Investigators: |
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Researcher Co-Investigators: |
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Project Partners: |
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Department: |
Chemistry |
Organisation: |
University of Warwick |
Scheme: |
Standard Research |
Starts: |
01 November 2012 |
Ends: |
31 October 2015 |
Value (£): |
313,668
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EPSRC Research Topic Classifications: |
Chemical Biology |
Gas & Solution Phase Reactions |
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EPSRC Industrial Sector Classifications: |
No relevance to Underpinning Sectors |
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Related Grants: |
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Panel History: |
Panel Date | Panel Name | Outcome |
08 Sep 2011
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EPSRC Physical Sciences Chemistry - September 2011
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Announced
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Summary on Grant Application Form |
The objective of this proposal is to study ultrafast UV-laser-induced dynamics in the DNA bases adenine and guanine as a stepping stone towards the nucleosides adenosine and guanosine. Funding will enable the PI to implement laser desorption into his laboratory so that these nucleosides can be brought into vacuum without decomposition and hence their ultrafast photochemistry studied in the gas-phase for the first time. Complementary high level calculations will provide critical guidance to interpreting the experimental results whilst posing new challenges to theoreticians as these studies will explore the complex interplay between multiple reaction paths and the ways these paths are coupled with one another with increasing molecular complexity. The PI, CoI and RCoI are ideally placed to undertake this exciting and ambitious research, which will begin to bridge the gap between the photochemistry of the DNA bases and that of nucleosides, and ultimately help elucidate the 'molecular mechanisms of the photostability of life'.
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Key Findings |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
Summary |
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Date Materialised |
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Sectors submitted by the Researcher |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Project URL: |
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Further Information: |
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Organisation Website: |
http://www.warwick.ac.uk |