| EPSRC Reference: |
EP/S030697/1 |
| Title: |
Mesoscale modelling with Fluctuating Finite Element Analysis (FFEA) |
| Principal Investigator: |
Harris, Dr S |
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| Department: |
Physics and Astronomy |
| Organisation: |
University of Leeds |
| Scheme: |
Overseas Travel Grants (OTGS) |
| Starts: |
03 May 2019 |
Ends: |
02 January 2020 |
Value (£): |
19,214
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| No relevance to Underpinning Sectors |
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Summary on Grant Application Form |
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There is a community consensus that "Structural biology is transitioning from a largely molecular perspective to a much wider range of length scales", as a result of developments in 3D cellular imaging tools such as cryo-Electron Microscopy and Tomography. Fluctuating Finite Element Analysis (FFEA) is a novel mesoscale biomolecular simulation tool developed by our research team at Leeds which is specifically designed for biomolecular modelling based on structural data from cryo-EM and cryo-ET. Through this travel grant I will build collaborations with key computational (Amaro), experimental (Chiu and Fire) and theoretical (Benham) groups to broaden the range of biological questions addressable with FFEA by performing preliminary calculations on cytoplasmic dynein and extrachromosomal DNA (eccDNA). The aim is to build an international community of FFEA users by ensuring usability and compatibility with other codes.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.leeds.ac.uk |