| EPSRC Reference: |
EP/V048368/1 |
| Title: |
Enantioconvergent Multi-Component Reactions. |
| Principal Investigator: |
Lawrence, Professor AL |
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| Department: |
Sch of Chemistry |
| Organisation: |
University of Edinburgh |
| Scheme: |
Standard Research - NR1 |
| Starts: |
29 April 2021 |
Ends: |
28 February 2023 |
Value (£): |
202,196
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| No relevance to Underpinning Sectors |
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Summary on Grant Application Form |
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Asymmetric synthesis is the branch of synthetic chemistry associated with making molecules in single-handed form (i.e., left-handed or right-handed form). The aim of this project is to experimentally establish a new concept in asymmetric synthesis called enantioconvergent multi-component reactions. This will represent a completely new method for accessing single-handed materials starting from mixtures of left- and right-handed molecules. Thanks to a statistical phenomenon known as the Horeau Principle, this new method will result in single-handed materials in exceptionally high purity. The ability to synthesise these left/right-handed molecules in pure form is vitally important, particularly for the pharmaceutical industry. This is because biological molecules exhibit handedness and the left-handed and right-handed form of a chemical (i.e., a drug/medicine) often interact very differently with living organisms.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.ed.ac.uk |