| EPSRC Reference: |
GR/J02964/01 |
| Title: |
THE SYNTHESIS AND PROPERTIES OF REDOX-GATED ION CHANNELS |
| Principal Investigator: |
Eisenthal, Professor R |
| Other Investigators: |
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| Project Partners: |
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| Department: |
Biology |
| Organisation: |
University of Bath |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
01 July 1993 |
Ends: |
30 June 1995 |
Value (£): |
78,940
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| EPSRC Research Topic Classifications: |
| Materials Synthesis & Growth |
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Summary on Grant Application Form |
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The programme sets out to synthesise novel redox-gated channel forming peptides based on the introduction of the ferrocene moiety. These peptides will be incorporated into lipid bilayers and the channel gating properties will be investigated. the effects of varying the oxidation state of the ferrocene moiety of the peptides on channel properties will be measured. The channels will be characterised in terms of conductance, open times and ion selectivity. These peptides may provide novel switching systems in which changes in the redox state of the membrane environment can be translated into electrical signals.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.bath.ac.uk |