EPSRC Reference: |
GR/J73704/01 |
Title: |
SEQUENCE DEPENDENT DNA STRUCTURE |
Principal Investigator: |
Hunter, Professor CA |
Other Investigators: |
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Researcher Co-Investigators: |
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Project Partners: |
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Department: |
Chemistry |
Organisation: |
University of Sheffield |
Scheme: |
Standard Research (Pre-FEC) |
Starts: |
24 November 1994 |
Ends: |
23 November 1997 |
Value (£): |
17,066
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EPSRC Research Topic Classifications: |
Biological & Medicinal Chem. |
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EPSRC Industrial Sector Classifications: |
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Related Grants: |
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Panel History: |
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Summary on Grant Application Form |
(1) Calculate the - interactions in single base-pair steps for all possible combinations base-pairs in all possible conformations.(2) Calculate the conformational restrictions imposed by the backbone.(3) Determine low energy conformations for longer DNA sequences.(4) Use these calculations to investigate the molecular basis of sequence-specific DNA recognition by proteins and drugs.
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Key Findings |
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Potential use in non-academic contexts |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
Summary |
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Date Materialised |
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Sectors submitted by the Researcher |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Project URL: |
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Further Information: |
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Organisation Website: |
http://www.shef.ac.uk |