| EPSRC Reference: |
GR/K08444/01 |
| Title: |
ASYMMETRIC SYNTHESIS OF CHIRAL-AT-METAL ORGANOMETALLICS |
| Principal Investigator: |
Taylor, Professor PC |
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| Department: |
Chemistry |
| Organisation: |
University of Warwick |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
12 December 1995 |
Ends: |
11 December 1998 |
Value (£): |
6,283
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Summary on Grant Application Form |
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A three phase programme directed at the catalytic asymmetric synthesis of chiral-at-metal organometallics is described.In phase 1 prochiral titanocene dichlorides will be reacted first with chiral Lewis acids the with nucleophilies. The asymmetric induction will be measured.In phase 2 the successful chiral Lewis acids will be used with a range of other metallocene derivatives. The potential of the products will be assessed using two bench mark reactions, polymerisation of polypropylene and asymmetric reduction of imines.In phase 3 the introduction of silylated and stannylated nucleophiles will be expoilted to realise the goal of catalytic asymmetric synthesis of potentially important asymmetric catalysts.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.warwick.ac.uk |