| EPSRC Reference: |
GR/K76160/01 |
| Title: |
STABLE CARBENES AS STRONG BASES |
| Principal Investigator: |
Alder, Professor R |
| Other Investigators: |
|
| Researcher Co-Investigators: |
|
| Project Partners: |
|
| Department: |
Chemistry |
| Organisation: |
University of Bristol |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
01 October 1996 |
Ends: |
30 September 1999 |
Value (£): |
145,610
|
| EPSRC Research Topic Classifications: |
| Chemical Synthetic Methodology |
|
|
| EPSRC Industrial Sector Classifications: |
|
| Related Grants: |
|
| Panel History: |
|
|
Summary on Grant Application Form |
|
A range of imidazol-2-ylidenes, including a variety of chiral structures will be prepared. Their pKa values will be determined and their reactivity as bases in promoting carbonyl group and elimination reactions will be investigated, including their reactivity as nucleophiles and the enantioselectivities of chiral examples in a range of demanding situations. The preparation of other diaminocarbenes will be sought and the redox chemistry of these species will be studied.Possible synthetic routes to imidazol-2-ylidenes and dihydroimidazol-2-ylidenes through cycloaddition reactions from carbodimides will be sought.
|
|
Key Findings |
|
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
|
|
Potential use in non-academic contexts |
|
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
|
|
Impacts |
|
| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
|
| Date Materialised |
|
|
|
|
Sectors submitted by the Researcher |
|
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
|
| Project URL: |
|
| Further Information: |
|
| Organisation Website: |
http://www.bris.ac.uk |