| EPSRC Reference: |
GR/K81027/01 |
| Title: |
SYNTHESIS OF NATURALLY OCCURING ENEDIYNES |
| Principal Investigator: |
Caddick, Professor S |
| Other Investigators: |
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| Project Partners: |
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| Department: |
Chemistry |
| Organisation: |
University of Sussex |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
23 January 1997 |
Ends: |
22 July 1999 |
Value (£): |
94,380
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| EPSRC Research Topic Classifications: |
| Chemical Synthetic Methodology |
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Summary on Grant Application Form |
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The aim of the proposed research is to develop a new synthetic approach to biologically important, naturally occuring enediynes. The work will involve using recently developed methodolgy for the preparation of fully functionalised A/B ring precursor. Several approaches to the construction of the central A/B ring systems will then be examined with the aim of preparing an advanced intermediate for the completion of the total synthesis. Further progress will involve the transformation of the advanced intermediate to a naturally occurring target, Neocarzinostatin.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.sussex.ac.uk |