| EPSRC Reference: |
GR/K88293/01 |
| Title: |
RING-EXPANSION ROUTES TO CYCLIC DIFLOUROKETONES VIA (3,3)-SIGMATROPIC REARRANGEMENTS |
| Principal Investigator: |
Percy, Professor JM |
| Other Investigators: |
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| Department: |
School of Chemistry |
| Organisation: |
University of Birmingham |
| Scheme: |
ROPA |
| Starts: |
01 October 1997 |
Ends: |
30 September 2000 |
Value (£): |
60,753
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| EPSRC Research Topic Classifications: |
| Chemical Synthetic Methodology |
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Summary on Grant Application Form |
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The proposed programme will develop novel and general routes to cyclic fluoroketones using ring expansion reactions. Exocyclic difluoroenol ethers will be synthesised using known procedures and the efficiency of [3, 3]-claisen rearrangement will be determined. Metallated difluoroenol carbamate chemistry will be used to synthesise a range of compounds capable of undergoing oxy-Cope rearrangement systems will be determined by varying the correlating the efficiency of rearrangement with the polar character of the 1, 5-dien-3-ol and. A wide range of cyclic difluoroketones will be generated in this way.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.bham.ac.uk |