Details of Grant 

EPSRC Reference:	GR/L35355/01
Title:	NUCLEOBASE-LIGAND CONJUGATES: BUILDING BLOCKS FOR SUPRAMOLECULAR COORDINATION CEMISTRY
Principal Investigator:	Houlton, Professor A
Other Investigators:
Researcher Co-Investigators:
Project Partners:
Department:	School of Chemistry
Organisation:	Newcastle University
Scheme:	Standard Research (Pre-FEC)
Starts:	01 October 1997	Ends:	30 September 2000	Value (£):	43,940
EPSRC Research Topic Classifications:	Co-ordination Chemistry
EPSRC Industrial Sector Classifications:	No relevance to Underpinning Sectors
Related Grants:
Panel History:
Summary on Grant Application Form
1) To establish synthetic routes for the preparation of novel metal-nucleobase complexes which retain the ability for intermolecular interactions via base-pair hydrogen bonding. To elucidate the molecular structure of the complexes in the solution- and solid-state using single crystal X-ray crystallography and n.m.r spectroscopy.2) To explore the reactivity of complexes prepared in (1) with unmodified nucleobases with the aim of synthesising self-complementary and non-complementary metallated-dinucleobase sequences. Determine the intermolecular interactions associated with these species in solution and the solid state.3) Evaluate the potential of the compounds prepared in (2) as molecular-based sensing agents for nucleoside phosphate anions.
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Organisation Website:	http://www.ncl.ac.uk