EPSRC Reference: |
GR/L60333/01 |
Title: |
THE POTENTIAL OF FEMTOSECOND LASER MASS SPECTROMETRY (FLMS) FOR ULTRA-TRACE ANALYSIS OF ATOMS AND MOLECULES |
Principal Investigator: |
Ledingham, Professor K |
Other Investigators: |
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Researcher Co-Investigators: |
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Project Partners: |
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Department: |
School of Physics and Astronomy |
Organisation: |
University of Glasgow |
Scheme: |
Standard Research (Pre-FEC) |
Starts: |
01 February 1998 |
Ends: |
31 March 2000 |
Value (£): |
176,592
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EPSRC Research Topic Classifications: |
Analytical Science |
Instrumentation Eng. & Dev. |
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EPSRC Industrial Sector Classifications: |
No relevance to Underpinning Sectors |
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Related Grants: |
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Panel History: |
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Summary on Grant Application Form |
Multiphoton mass spectrometry (ns REMPI) has proved to be a very important procedure for the analysis of atoms and molecules at ultra-trace levels. Two areas for which ns REMPI has been less effective are in the detection of thermally labile molecules (dissociative) and in quantitative surface analysis of elements. On the other hand we have shown in a number of exploratory, peer reviewed, experiments at RAL and FORTH (Crete) that femotsecond laser mass spectrometry (FLMS) has enormous potential in this field. In particular FLMS has the potential of being a laser technique with an ionisation probability for both atoms and molecules which is independent of wavelength, intensity and IP (100% ionisation efficiency). To substantiate this further we wish to undertake a series of experiments using FLMS for (a) surface analysis of semiconductor and metal samples, (b) study of gas phase small molecules (c) study of aromatic and nitroaromatic molecules, (d) the analysis of organometallic molecules, and (e) the analysis of medium mass biomolecules (peptides). We will determine the improved sensitivity, identify any problems with interferences and in particular the potential of FLMS as an ultra-trace quantitative technique.
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Key Findings |
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Potential use in non-academic contexts |
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Impacts |
Description |
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Summary |
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Date Materialised |
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Sectors submitted by the Researcher |
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Project URL: |
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Further Information: |
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Organisation Website: |
http://www.gla.ac.uk |