| EPSRC Reference: |
GR/L70745/01 |
| Title: |
ROPA:AN INTEGRATED SYSTEM FOR THE COLLECTION & ASSAY OF SKIN EXUDATE |
| Principal Investigator: |
Heard, Dr CM |
| Other Investigators: |
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| Project Partners: |
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| Department: |
Welsh School of Pharmacy |
| Organisation: |
Cardiff University |
| Scheme: |
ROPA |
| Starts: |
01 October 1997 |
Ends: |
31 December 1999 |
Value (£): |
96,778
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| EPSRC Research Topic Classifications: |
| Instrumentation Eng. & Dev. |
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| EPSRC Industrial Sector Classifications: |
| No relevance to Underpinning Sectors |
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Summary on Grant Application Form |
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Compounds circulating in bloodstream are known to exude through skin. Molecularly imprinted polymer (MIP) are an established means of preparing sorbents of very high specificity. We propose to investigate the feasibility of entrapping skin exudates using MIPs in dermal devices, for use in saturation assays. The potential of such systems is very large and diverse, eg: 'domestic' therapeutic drug monitoring, detection of drug abuse and workplace exposure (eg absorption of organophosphates by military personnel). MIPs will be preapred for a series of compounds and Franz diffusion cells containing human skin will be used in the reverse mode to determine efflux.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.cf.ac.uk |