| EPSRC Reference: |
GR/L72961/01 |
| Title: |
ROPA: NOVEL NANOPARTICLES FOR PULMONARY DRUG ADMINISTRATION |
| Principal Investigator: |
Kellaway, Professor I |
| Other Investigators: |
|
| Researcher Co-Investigators: |
|
| Project Partners: |
|
| Department: |
Welsh School of Pharmacy |
| Organisation: |
Cardiff University |
| Scheme: |
ROPA |
| Starts: |
01 November 1997 |
Ends: |
31 October 1999 |
Value (£): |
71,764
|
| EPSRC Research Topic Classifications: |
|
| EPSRC Industrial Sector Classifications: |
| No relevance to Underpinning Sectors |
|
|
| Related Grants: |
|
| Panel History: |
|
|
Summary on Grant Application Form |
|
This proposal will investigate a novel process for the production of pressurised metered dose inhaler formualtions. Novel nanoparticles will be synthsised from polymers, currently under investigation as drug carriers, and containing a peptidergic drug. An L2 phase micellar system will from the template for the conversion of the polymers into nanoparticels following polar solvent addition and crosslinking. Microemulsion chacteristics will be understood prior to stability studies in hydrofluoroalkane propellants. The final phase will involove aerosolisation studies as assessed by cascade impaction techniques and the potential to control the release of the peptidergic drug from the deposited fraction will be evaluated.
|
|
Key Findings |
|
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
|
|
Potential use in non-academic contexts |
|
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
|
|
Impacts |
|
| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
|
| Date Materialised |
|
|
|
|
Sectors submitted by the Researcher |
|
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
|
| Project URL: |
|
| Further Information: |
|
| Organisation Website: |
http://www.cf.ac.uk |