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Details of Grant 

EPSRC Reference: GR/L73180/01
Title: NEW STRATEGIES IN THE DEVELOPMENT OF MICRO-TOTAL ANALYSIS SYSTEMS
Principal Investigator: de Mello, Professor AJ
Other Investigators:
Researcher Co-Investigators:
Project Partners:
Department: Chemistry
Organisation: Imperial College London
Scheme: Standard Research (Pre-FEC)
Starts: 01 October 1997 Ends: 30 September 2000 Value (£): 89,694
EPSRC Research Topic Classifications:
Analytical Science
EPSRC Industrial Sector Classifications:
No relevance to Underpinning Sectors
Related Grants:
Panel History:  
Summary on Grant Application Form
The aim of this research proposal is to advance existing technology and develop new methodologies in key areas of micro-TAS science. The research programme will commence with the construction of a microfabrication laboratory. This facility provides the means to construct test and characterise prototype micro-TAS. With the applicants expertise in microfabrication, novel electrophoresis microchips will be made to perform fast separations of small molecular species (separation of molecular mixtures on timescales <1s). Concurrent to the development of microfabrication protocols, an electrokinetic switching device will be built. This allows facile manipulation of sample within micro-TAS. In addition, a confocal, fluorescence imaging system will be constructed to provide high-sensitivity detection.The primary focus of this proposal is the integration of additional analysis components. This element will be key to the eventual versatility and success of micro-TAS. Sample filters, reactors, temperature sensors and integrated light sources will all be fabricated using novel protocols. These developments truly embrace the concepts of miniaturisation and automation. The ultimate aim is to apply micro-TAS technology to on-line monitoring of the C-41 photographic process. Dedicated micro-TAS will be constructed to address this problem. Devices of this kind are of great significance to many industrial and clinical applications.
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Organisation Website: http://www.imperial.ac.uk