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Details of Grant 

EPSRC Reference: GR/L87484/01
Title: JREI:OPEN ACCESS LC-MASS SPECTROMETRY FACILITY
Principal Investigator: Cullis, Professor PM
Other Investigators:
Eaton, Dr G Holloway, Professor J
Researcher Co-Investigators:
Project Partners:
Safepharm Laboratories Ltd Waters Corporation / Micromass U K Ltd
Department: Chemistry
Organisation: University of Leicester
Scheme: JREI
Starts: 23 March 1998 Ends: 22 March 2001 Value (£): 99,000
EPSRC Research Topic Classifications:
Asymmetric Chemistry Biological & Medicinal Chem.
Chemical Synthetic Methodology Electrochemical Science & Eng.
Gas & Solution Phase Reactions
EPSRC Industrial Sector Classifications:
Chemicals
Related Grants:
Panel History:  
Summary on Grant Application Form
The Department of Chemistry at Leicester University has a very active research school of over 80. The research areas of the Department are many and varied including organic synthesis, bio-organic and bio-inorganic chemistry, fluorine chemistry, organometallic chemistry, catalysis, electro-chemistry and organophosphorus chemistry. The Department has in excess of 3 million grant income, that includes approximately 1.5 million from the EPSRC, including a number of current grants in strategic areas identified by Technology Foresight. The research school has a very high productivity (over 130 papers annually). We are seeking to support and enhance this research programme by updating the infrastructure for mass spectrometry. This application is for funds to purchase a Quattro LC Open Access System Micromass UK Ltd) that would bring capabilities not currently available in the Department (MS-MS; -ve ion ESMS; LC-MS) and would allow mass spectrometry to be used in an entirely novel manner to monitor reactions in situ. The case for this instrument embraces three distinct needs:* to provide quadrupole electrospray facilities for bio-organic and bio-inorganic chemistry, including negative ion ESMS for oligonucleotides;* to provide MS-MS capabilities;to provide routine open-access low resolution mass spectrometry, including unique opportunities for rapid screening of reaction products, for all of the research activities of the organic and inorganic preparative chemists.
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Further Information:  
Organisation Website: http://www.le.ac.uk