| EPSRC Reference: |
GR/M28149/01 |
| Title: |
A NEW SYSTEM FOR CATALYTIC ASYMMETRIC EPOXIDATION |
| Principal Investigator: |
Page, Professor P |
| Other Investigators: |
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| Project Partners: |
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| Department: |
Chemistry |
| Organisation: |
Loughborough University |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
01 November 1998 |
Ends: |
31 October 2001 |
Value (£): |
152,617
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| No relevance to Underpinning Sectors |
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Summary on Grant Application Form |
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The aim of this project is the development of a new system for catalytic asymmetric epoxidation, based upon a homogeneous procedure recently developed in our laboratories, permitting catalytic enantioselective oxygen transfer under near-ambient conditions on a very short timescale (<2h). The chemistry involved is novel, uses inexpensive reagents, no transition metals, and is amenable to scale up. In preliminary experimentation we have achieved ees of up to 73% for trans-stilbene as substrate, in very clean 1 hour reactions carried out at 0 C or at room temperature, in the presence of as little as 0.3 mol% of catalyst.Maximization of the potential of these catalysts for asymmetric epoxidation is the central objective of this proposal.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.lboro.ac.uk |