EPSRC Reference: |
GR/M33730/01 |
Title: |
COMPUTATIONAL SIMULATIONS MORPHOGENETIC PROCESSES TO EVOLVE REALISTIC LIFE-FORMS USING ADAPTIVE 3D MESHES |
Principal Investigator: |
Berzins, Professor M |
Other Investigators: |
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Researcher Co-Investigators: |
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Project Partners: |
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Department: |
Sch of Computing |
Organisation: |
University of Leeds |
Scheme: |
Standard Research (Pre-FEC) |
Starts: |
01 April 1999 |
Ends: |
30 April 2002 |
Value (£): |
174,173
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EPSRC Research Topic Classifications: |
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EPSRC Industrial Sector Classifications: |
No relevance to Underpinning Sectors |
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Related Grants: |
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Panel History: |
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Summary on Grant Application Form |
While molecular genetics has revealed the patterns of regulatory gene activities involved in embryonic development, we do not yet understand how these result in the morphogenetic processes that give rise to the morphologies of different species, nor how these evolve.Since experimental study on large-scale morphological evolution is not possible, computer simulation becomes a more important method of investigation. Developing a realistic method of simulating morphogenesis and its evolution will have important implications for both biology and engineering. The overall aim of the proposed project is to develop such a simulation motivated by recent biological models of morphogenesis and gene circuits and to apply this model both to enhance our understanding of the biology and to demonstrate its potential application within engineering, through the use of robust computational science methods and software. The computational algorithms will be adaptive unstructured three-dimensional meshes to follow the evolution of the surfaces combined with fast, iterative methods to solve the equations arising from the mathematical models of Cummings.The novelty and value of this work is the construction and study of a self-oragnising, evolving system with realistic three-dimensional constraints that simulate organismic life-cycles.
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Key Findings |
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Potential use in non-academic contexts |
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Impacts |
Description |
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Summary |
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Date Materialised |
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Sectors submitted by the Researcher |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Project URL: |
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Further Information: |
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Organisation Website: |
http://www.leeds.ac.uk |