EPSRC Reference: |
GR/M44187/01 |
Title: |
BROADLY TUNABLE OPOS FOR MULTIPHOTON MICROSCOPY |
Principal Investigator: |
Ferguson, Professor AI |
Other Investigators: |
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Researcher Co-Investigators: |
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Project Partners: |
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Department: |
Physics |
Organisation: |
University of Strathclyde |
Scheme: |
Standard Research (Pre-FEC) |
Starts: |
01 April 1999 |
Ends: |
31 December 2001 |
Value (£): |
196,180
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EPSRC Research Topic Classifications: |
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EPSRC Industrial Sector Classifications: |
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Related Grants: |
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Panel History: |
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Summary on Grant Application Form |
Multiphoton microscopy is in the process of revolutionising imaging in the biological sciences and is likely to have an effect in non-destructive testing and analysis in the physical sciences. In multiphoton imaging, depth sectioning is made possible by use of multiphoton absorption in fluorescent materials. In order for the process to be efficient a source of femtosecond pulses is required with a repetition rate comparable to the inverse of the fluorescence lifetime of the fluorophore. Although the technique works extremely well at selected wavelengths there is a strong desire for a broadly tunable source which can be optimised for the system being investigated. In many systems the excitation and fluorescence wavelength gives important information on the detail of processes within the sample. There are very tight constraints on the efficiency, compactness and reliability of the excitation source which makes an all solid state synchronously pumped optical parametric oscillator (OPO) an excellent solution. This project will be primarily concerned with demonstrating the feasibility of a sub-picosecond OPO based on periodically poled KTP for this purpose. This source will be incorporated into an existing scan head which will provide a unique capability.
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Key Findings |
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Potential use in non-academic contexts |
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Impacts |
Description |
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Summary |
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Date Materialised |
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Sectors submitted by the Researcher |
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Project URL: |
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Further Information: |
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Organisation Website: |
http://www.strath.ac.uk |