| EPSRC Reference: |
GR/M52533/01 |
| Title: |
DEVELOPMENT OF A NOVEL METHOD OF ULTRA-FAST MAGNETIC RESONANCE IMAGING FOR QUANTITATIVE IMAGING OF TUMOURS |
| Principal Investigator: |
Leach, Professor MO |
| Other Investigators: |
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| Department: |
Division of Radiotherapy and Imaging |
| Organisation: |
Institute of Cancer Research |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
15 November 1999 |
Ends: |
14 November 2002 |
Value (£): |
152,263
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| EPSRC Research Topic Classifications: |
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| EPSRC Industrial Sector Classifications: |
| Healthcare |
No relevance to Underpinning Sectors |
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Summary on Grant Application Form |
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Although it is now possible to cure a considerable fraction of all cancer patients, it is still often difficult to predict the outcome of radio-or chemotherapy and hence tailor treatment for an individual. One factor known to be important is the set of physical and structural properties that comprise a tumour's micro-environment . Magnetic Resonance Imaging (MRI) has already demonstrated great potential for investigating non-invasively many of the components of this micro-environment, but in order to maximise the information obtained from such studies, it is necessary to increase the speed of MRI measurements. In a collaboration between two institutions and five different disciplines, the applicants seek to address these issues by exploiting a new ultra-fast imaging technique called Burst, which has a number of extremely attractive properties. The goal of this project is to develop improved Burst pulse sequences, yielding higher resolution images with better signal-to-noise than currently available. Work will be performed on a 1.5 T clinical scanner, leading to patient trials, and on a new 11.7 T research system. In both cases, the ultra-fast images obtained will be used to measure quantitatively key parameters of the tumour micro-environment.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.icr.ac.uk |