| EPSRC Reference: |
GR/N13937/01 |
| Title: |
MESOPOROUS SILICAS FOR COMBINATORIAL CHEMISTRY |
| Principal Investigator: |
Attard, Professor G |
| Other Investigators: |
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| Researcher Co-Investigators: |
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| Project Partners: |
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| Department: |
Sch of Chemistry |
| Organisation: |
University of Southampton |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
01 January 2001 |
Ends: |
31 December 2002 |
Value (£): |
115,898
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| EPSRC Research Topic Classifications: |
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| EPSRC Industrial Sector Classifications: |
| Chemicals |
Pharmaceuticals and Biotechnology |
| No relevance to Underpinning Sectors |
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Summary on Grant Application Form |
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The proposed research is based on a method of producing ultra-high surface area silicas (800 m^2/g to 1500 m^2/g) that we have pioneered at Southampton. These silicas have pores of uniform diameter (1.7 nm to 16 nm) disposed on a hexagonal lattice. We now seek to develop these silicas as new types of supports for combinatorial chemistry applications. The novel supports would combine a substantially higher loading capacity than is possible with existing commercial supports with a maximum operating temperature that is determined only by the thermal stability of the species attached to it. We propose to produce both particulate and laminar supports. In the latter case free-standing monolithic discs as well as supported thin films will be produced. The key elements of the work programme are: (i) to develop reliable methods of processing monolithic discs and supported films (ii) to develop protocols for the functionalisation of the novel supports using bifunctional silylating agents (iii) to benchmark the performance of the novel supports; this will entail producing 3 model libraries selected to demonstrate performance relative to commercial beads, performance in reactions that require high temperature and performance in continuous flow systems.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.soton.ac.uk |