| EPSRC Reference: |
GR/N23608/01 |
| Title: |
ROPA: THE POTENTIAL OF IN SITU ENGINEERED LIGAMENT REPL'T USING BIOENHANCED POLYESTER WITH PLASMA TREAT'T |
| Principal Investigator: |
Seedhom, Dr BB |
| Other Investigators: |
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| Department: |
School of Medicine |
| Organisation: |
University of Leeds |
| Scheme: |
ROPA |
| Starts: |
15 January 2001 |
Ends: |
14 January 2003 |
Value (£): |
102,694
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| EPSRC Research Topic Classifications: |
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| EPSRC Industrial Sector Classifications: |
| Healthcare |
No relevance to Underpinning Sectors |
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Summary on Grant Application Form |
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Plasma treated polyester is rendered hydrophilic which considerably enhances the treated material's ability to attract synovial cells above that of untreated polyester. Treated and untreated yarns will be placed in culture and the number of cells adhering to both yarn types will be compared. Cell proliferation, their extent of differentiation and collagen biosynthesis will also be compared, when the yarns (and hence cells) are subjected to cyclic strains, while in culture. Results will reveal the potential of the treated material for use as a ligament scaffold for direct implantation, thus obviating the need for seeding and culture prior to implanting.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.leeds.ac.uk |