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Details of Grant 

EPSRC Reference: GR/N32570/01
Title: LIPOIC ACID BIOSYNTHESIS
Principal Investigator: Roach, Professor P
Other Investigators:
Researcher Co-Investigators:
Project Partners:
CEA - Atomic Energy Commission Lonza Osaka University
Department: Sch of Chemistry
Organisation: University of Southampton
Scheme: Standard Research (Pre-FEC)
Starts: 01 February 2001 Ends: 31 January 2003 Value (£): 120,156
EPSRC Research Topic Classifications:
Biological & Medicinal Chem.
EPSRC Industrial Sector Classifications:
Pharmaceuticals and Biotechnology
Related Grants:
Panel History:  
Summary on Grant Application Form
Living organisms make lipoic acid by a very direct route, using a reaction that would be difficult to achieve with synthetic chemistry. In order to understand the underlying chemistry of the biological process, we will examine the biochemical machinery of the cell and identify the protein components required for the transfer of sulphur from a simple precursor to form lipoic acid.
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Further Information:  
Organisation Website: http://www.soton.ac.uk