EPSRC Reference: |
GR/R03204/01 |
Title: |
IMI: Activated Carbon Haemoadsorbents For the Removal of Middle Molecular Weight and Other Toxins From Blood |
Principal Investigator: |
Hellgardt, Professor K |
Other Investigators: |
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Researcher Co-Investigators: |
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Project Partners: |
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Department: |
Chemical Engineering |
Organisation: |
Loughborough University |
Scheme: |
LINK |
Starts: |
01 October 2000 |
Ends: |
30 September 2003 |
Value (£): |
248,179
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EPSRC Research Topic Classifications: |
Medical science & disease |
Separation Processes |
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EPSRC Industrial Sector Classifications: |
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Related Grants: |
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Panel History: |
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Summary on Grant Application Form |
The research programme comprises: (1) The design and manufacture of novel heamoadsorbents based on uncoated polymer pyrolised activated carbons. (2) The development of prototype extracorporeal devices for removal of uraemic toxins from the circulation of patients with renal and multi-organ failure. (3) Medical grade activated carbons will be evaluated during in vitro studies to demonstrate the effective removal of low and middle molecular weight uraemic toxins from blood. (4) Haemo/biocompatibility of the adsorbents in order to prevent the formation of microemboli will be investigated. (5) Regeneration of spent adsorption columns will be studied to evaluate the potential for repetitive use. (6) A preliminary cost-benefit analysis will be performed of the extracorporeal adsorption technique for the treatment of patients with acute and chronic renal failure.
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Key Findings |
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Potential use in non-academic contexts |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
Description |
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Summary |
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Date Materialised |
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Sectors submitted by the Researcher |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Project URL: |
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Further Information: |
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Organisation Website: |
http://www.lboro.ac.uk |