| EPSRC Reference: |
GR/R16587/01 |
| Title: |
Design and Synthesis of Novel Lanthanide Complexes |
| Principal Investigator: |
Amoroso, Dr AJ |
| Other Investigators: |
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| Researcher Co-Investigators: |
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| Project Partners: |
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| Department: |
Chemistry |
| Organisation: |
Cardiff University |
| Scheme: |
Fast Stream |
| Starts: |
01 August 2001 |
Ends: |
31 July 2004 |
Value (£): |
66,502
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| EPSRC Research Topic Classifications: |
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| EPSRC Industrial Sector Classifications: |
| Chemicals |
Electronics |
| Pharmaceuticals and Biotechnology |
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Summary on Grant Application Form |
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There is currently great interest in lanthanide complexes; they haw potential uses in luminescence studies (photo-cells, fluorometric assays, lasers, optical data transportation and VDUs) and in paramagnetic materials (molecular magnets, shift reagents and MRI contrast agents).This project involves the synthesis of a series of ligands suitable for the complexation of lanthanides metals and it will be shC1.vn that ligand modification is easy and can allow systematic investigations into the relationship of between the chemical structure and physical properties of various lanthanide ions. Particular interest will be shC1.vn for Eu and Tb complexes, suitable for luminescent tags/sensors, and Gd complexes for use as MRI contrast agents.The ligand systems of interest are primarily based upon poly-pyridine systems, the synthesis for which is based on good literature precedence leading to a high confidence in success. Tying together several known features is a novel way, interesting results are expected. Significantly, the project then aims to extend these types of ligands to include quinoline functions. By inclusion of their rigid pi framework we can utilise their steric and photochemical properties and by systematically feeding back results from our measurements into our design, we will improve the complex's desired properties.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.cf.ac.uk |