Details of Grant 

EPSRC Reference:	GR/R23718/01
Title:	Molecular Sensor Array For Exobiology Application
Principal Investigator:	Cullen, Professor DC
Other Investigators:	Sims, Professor MR Grant, Professor W
Researcher Co-Investigators:
Project Partners:
Department:	Inst of Bioscience & Technology
Organisation:	Cranfield University
Scheme:	Fast Stream
Starts:	17 September 2001	Ends:	16 March 2003	Value (£):	61,899
EPSRC Research Topic Classifications:	Chemical Biology Instrumentation Eng. & Dev.
EPSRC Industrial Sector Classifications:	Aerospace, Defence and Marine
Related Grants:
Panel History:
Summary on Grant Application Form
Exobiology aims to study the origin, evolution and distribution of both past and present life in the Universe. A key objective of exobiology lander missions, e.g. to Mars and Europa. is the detection of biomarkers -molecules whose presence indicates the existence of either current or extinct life. To overcome limitations. of current analytical methods to biomarker detection, we propose demonstration of a robust molecular-recognition sensor array for exobiology biomarkers and determination of its performance envelope. This will be achieved by assembling components that have been demonstrated individually in previous or current research projects. The major components are (i) robust artificial molecular receptors comprised of molecular imprinted polymer (MIP) recognition systems and (ii) a sensor array comprised of both optical and electrochemical sensor elements. These components will be integrated together using ink-jet printing technology coupled with in situ photo-polymerisation of the MIPs. For demonstration, four model biomarkers are chosen as targets and represent various classes of potential biomarkers. Objectives of the proposed work are (i) show practical proof-of-concept. (ii) identify areas for further development and (iii) provide performance and design data for follow-up projects leading to exobiology missions.
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Organisation Website:	http://www.cranfield.ac.uk