EPSRC Reference: |
GR/R24890/01 |
Title: |
Single Bead Uv/Vis and Chiral Spectroscopy |
Principal Investigator: |
Bradley, Professor M |
Other Investigators: |
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Researcher Co-Investigators: |
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Project Partners: |
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Department: |
Sch of Chemistry |
Organisation: |
University of Southampton |
Scheme: |
ROPA |
Starts: |
01 October 2001 |
Ends: |
30 June 2003 |
Value (£): |
115,127
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EPSRC Research Topic Classifications: |
Analytical Science |
Combinatorial Chemistry |
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EPSRC Industrial Sector Classifications: |
Chemicals |
Pharmaceuticals and Biotechnology |
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Related Grants: |
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Panel History: |
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Summary on Grant Application Form |
The ability to measure UV/V is spectra and determine directly optical rotations of single beads would have a wide range of practical applications in analysis related to on bead synthesis. Using a CCD detector coupled to a microscope we will carry out a number of direct on bead studies. This will include the direct monitoring of specific solid phase transformations, the use of dyes as sensors, an investigation of changes in the hydrophobicity within the beads environment, and direct chiral interrogation probed by opticl rotation during asymmetric synthesis. These will be the first measurements of this type made directly on beads.
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Key Findings |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
Summary |
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Date Materialised |
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Sectors submitted by the Researcher |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Project URL: |
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Further Information: |
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Organisation Website: |
http://www.soton.ac.uk |