| EPSRC Reference: |
GR/S09906/01 |
| Title: |
Physics-based image interpretation to aid the detection of early signs of retinopathies |
| Principal Investigator: |
Claridge, Professor E |
| Other Investigators: |
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| Project Partners: |
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| Department: |
School of Computer Science |
| Organisation: |
University of Birmingham |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
01 February 2003 |
Ends: |
30 June 2005 |
Value (£): |
119,722
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| EPSRC Research Topic Classifications: |
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| EPSRC Industrial Sector Classifications: |
| Healthcare |
Information Technologies |
| No relevance to Underpinning Sectors |
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Summary on Grant Application Form |
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Diabetic retinopathy is the largest single cause of blindness amongst working age population in the United Kingdom. If pathological changes are detected early, appropriate measures taken to prevent loss of sight are likely to be more effective.This project aims to develop and validate a new physics based image interpretation method for the ocular fundus and to evaluate its potential in detecting early signs of diabetic retinopathies. An understanding of the physical interaction of light with ocular tissue is utilised to formulate a mathematical model capable of predicting colours which correspond to different tissue composition. Colours in digitized clinical images will be interpreted through reference to this model, generating retinal maps which show separately the quantities and distribution of blood, retinal pigment and pathological exudates at every image point. In clinical use the maps would be viewed alongside the conventional image, helping clinical interpretation by highlighting changes, showing the presence of pathologies and removing the masking effect of melanin on small blood variations. For the patient, the new method would be no more onerous than current fundus photography, but the instant availability of the retinal maps would enhance the effectiveness of retinal photographic screening, allowing prompt feedback to the patient and referring medical staff.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.bham.ac.uk |