Details of Grant 

EPSRC Reference:	GR/S27276/01
Title:	Synchronising Angiogenesis and Tissue Regeneration
Principal Investigator:	Oreffo, Professor R
Other Investigators:	Clarke, Professor N
Researcher Co-Investigators:
Project Partners:	University of Wurzburg
Department:	Development Origin of Health and Disease
Organisation:	University of Southampton
Scheme:	Standard Research (Pre-FEC)
Starts:	01 January 2004	Ends:	30 September 2006	Value (£):	183,450
EPSRC Research Topic Classifications:	Tissue Engineering
EPSRC Industrial Sector Classifications:	Healthcare
Related Grants:	GR/S27269/01
Panel History:
Summary on Grant Application Form
Describe the proposed research in about 200 words.The need to stimulate angiogenesis is a critical requirement of future tissue engineering applications. Without extensive and co-ordinated format of new blood vessels many tissues will fail to form as a result of insufficient nutrient, cytokine and cell transport. The pivotal role of angiogenesis bone, liver, nerve, kidney, skin and other tissue regeneration strategies has been widely acknowledged and many researchers are working on the use of angiogenic factors to stimulate blood vessel formation. However, current methods have neglected the need to synchronise angiogenesis u the formation of the surrounding tissue. Our new concept is to independently control the stimulation of tissue repair and angiogenesis. We will demonstrate this concept by enhancing bone regeneration.
Key Findings
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Potential use in non-academic contexts
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Project URL:
Further Information:
Organisation Website:	http://www.soton.ac.uk