| EPSRC Reference: |
GR/S40503/01 |
| Title: |
The Invention of the Catalytic Alkenation of Carbonyl Compounds |
| Principal Investigator: |
Anderson, Professor JC |
| Other Investigators: |
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| Project Partners: |
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| Department: |
Sch of Chemistry |
| Organisation: |
University of Nottingham |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
01 October 2003 |
Ends: |
30 September 2006 |
Value (£): |
184,103
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| EPSRC Research Topic Classifications: |
| Catalysis & Applied Catalysis |
Chemical Synthetic Methodology |
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Summary on Grant Application Form |
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The impetus for this research is the need for the development of a catalytic alkenation of carbonyl compounds. The realisation of this research will provide an atom efficient process with benign waste.The formation of alkenes combining with it the formation of a carbon-carbon bond represents a fundamental bond construction in organic synthesis. Typically in the laboratory and industry this is performed with stoichiometric phosphoros or transition metal based reagents. Due to the stoichiometry this is expensive and wasteful. This proposal describes a new strategy that could generate a catalytic olefination using metal alkylidene/oxo chemistry and carbonyl compounds. Olefin metathesis has long been catalysed by transition metal complexes while the corresponding carbonyl metathesis reaction remains stoichiometric. We wish to investigate the conversion of the by-product of a transition metal mediated carbonyl olefination reaction, a metal oxo species, to a metal alkylidene, by cycloaddition and then retrocycloaddition with a suitable ketene. We propose to do this by careful investigation and tuning of new metal oxo complexes of tungsten, molybdenum, chromium and rhenium. The characterisation of such a process would lay the foundation for new green technology in organic synthesis.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.nottingham.ac.uk |