EPSRC Reference: |
GR/S41494/01 |
Title: |
Convariate-adjusted adaptive designs for binary for survival multi-treatment clinaical trials |
Principal Investigator: |
Coad, Dr D |
Other Investigators: |
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Researcher Co-Investigators: |
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Project Partners: |
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Department: |
Sch of Mathematical & Physical Sciences |
Organisation: |
University of Sussex |
Scheme: |
Standard Research (Pre-FEC) |
Starts: |
16 June 2003 |
Ends: |
15 September 2003 |
Value (£): |
2,460
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EPSRC Research Topic Classifications: |
Medical science & disease |
Statistics & Appl. Probability |
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EPSRC Industrial Sector Classifications: |
Healthcare |
Pharmaceuticals and Biotechnology |
No relevance to Underpinning Sectors |
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Related Grants: |
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Panel History: |
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Summary on Grant Application Form |
The project consists of two parts: Covariate-adjusted adaptive designs for comparing K>2 treatments with binary responses and Covariate-adjusted and designs for comparing K>2 treatments with survival responses . The aim is to extend the two-treatment designs of Rosenberger, Vidyashankar and agarwal (2001, J. Biopharm. Statist. 11, 227-236) and Rosenberger and Seshaiyer (1997, J. Biopharm. Statist. 7, 617-624). Delayed responses and staggered entry will be incorporated in both designs. The work will build on the general design for comparing K>2 treatments with continuous responses of Biswas and Coad (2002, Submitted to Biometrika). Designs of the type being studied are of direct relevance to pharmaceutical experimentation.
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Key Findings |
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Potential use in non-academic contexts |
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Impacts |
Description |
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Summary |
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Date Materialised |
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Sectors submitted by the Researcher |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Project URL: |
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Further Information: |
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Organisation Website: |
http://www.sussex.ac.uk |