| EPSRC Reference: |
GR/S60051/01 |
| Title: |
Novel methods for the synthesis of excitatory amino acids & the chemistry of novel silinones |
| Principal Investigator: |
Parsons, Professor P |
| Other Investigators: |
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| Researcher Co-Investigators: |
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| Project Partners: |
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| Department: |
Chemistry |
| Organisation: |
University of Sussex |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
01 October 2003 |
Ends: |
30 September 2006 |
Value (£): |
93,068
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| EPSRC Research Topic Classifications: |
| Chemical Synthetic Methodology |
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| EPSRC Industrial Sector Classifications: |
| Chemicals |
Pharmaceuticals and Biotechnology |
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| Related Grants: |
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| Panel History: |
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Summary on Grant Application Form |
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This research programme will involve the synthesis of the hitherto poorly described silinones. Novel silinones will be prepared and their general chemistry will be investigated including their conversion into amino acids. Photoaddition of the silinones to pyrrolines will be investigated allowing a rapid entry into the kainate skeleton. A synthesis of domoic acid will be undertaken which will involve a rearangement/silicon mediated fragmentation cascade as a key step.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.sussex.ac.uk |