EPSRC Reference: |
GR/S61812/01 |
Title: |
Molecular wrapping of proteins: novel building blocks for nanotechnology |
Principal Investigator: |
Mann, Professor S |
Other Investigators: |
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Researcher Co-Investigators: |
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Project Partners: |
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Department: |
Chemistry |
Organisation: |
University of Bristol |
Scheme: |
Standard Research (Pre-FEC) |
Starts: |
01 October 2004 |
Ends: |
30 September 2007 |
Value (£): |
184,893
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EPSRC Research Topic Classifications: |
Chemical Biology |
Materials Characterisation |
Materials Synthesis & Growth |
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EPSRC Industrial Sector Classifications: |
Healthcare |
Pharmaceuticals and Biotechnology |
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Related Grants: |
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Panel History: |
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Summary on Grant Application Form |
The central theme of the proposed work is that molecular wrapping of proteins such as myoglobin can be achieved using organo-functionalized oligomers of stable inorganic frameworks such as exfoliated nanoclusters of synthetic magnesium (organo)phyllosilicates. We intend to produce structurally and functionally intact wrapped protein molecules in the form of dispersed nanoparticles or nanostructured arrays and thin films with enhanced thermal stability. We aim to demonstrate and explore the nanotechnological potential of wrapped biomolecules through a focused study using archetypal proteins with functions such as oxygen binding, electron transport and enzyme catalysis.
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Key Findings |
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Potential use in non-academic contexts |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
Summary |
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Date Materialised |
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Sectors submitted by the Researcher |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Project URL: |
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Further Information: |
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Organisation Website: |
http://www.bris.ac.uk |