EPSRC Reference: |
GR/S80103/01 |
Title: |
Structural Modelling of the Biological Interface with Materials |
Principal Investigator: |
Harding, Professor J |
Other Investigators: |
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Researcher Co-Investigators: |
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Project Partners: |
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Department: |
Materials Science and Engineering |
Organisation: |
University of Sheffield |
Scheme: |
Standard Research (Pre-FEC) |
Starts: |
01 February 2005 |
Ends: |
31 July 2009 |
Value (£): |
520,850
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EPSRC Research Topic Classifications: |
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EPSRC Industrial Sector Classifications: |
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Related Grants: |
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Panel History: |
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Summary on Grant Application Form |
Bones teeth and shells are examples of biominerals. An organic scaffold controls how and where mineral crystals will nucleate and grow. The result is a complex material, which has characteristic structure at many lengthscales and unusual properties. An understanding of these properties is essential in medicine, where biocompatible prosthetics are needed. These materials also offer clues to how new materials and structures can be designed. Biomaterials self-assemble; under the right conditions ordered structures emerge from simple nanoscale components. The purpose of this project is to understand how all this happens. In particular, we wish to understand the interface between the organic part and the mineral which controls all this. The models developed during this project will be applied to specific problems in the areas of biodevices, biosensors, biominerals and nanomaterials. A consortium from three institutions, University College London, Cambridge and Warwick will collaborate in a four year project costing 1.3M pounds to develop and apply these models. The project will be closely connected to world-class experimental groups and industrial partners. The new methods and understanding will be disseminated to the academic community through a programme of workshops and meetings.
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Key Findings |
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Potential use in non-academic contexts |
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Impacts |
Description |
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Summary |
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Date Materialised |
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Sectors submitted by the Researcher |
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Project URL: |
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Further Information: |
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Organisation Website: |
http://www.shef.ac.uk |