| EPSRC Reference: |
EP/F025750/1 |
| Title: |
Transcostal High Intensity Focused Ultrasound for the Treatment of Cancer |
| Principal Investigator: |
Saffari, Professor N |
| Other Investigators: |
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| Researcher Co-Investigators: |
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| Project Partners: |
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| Department: |
Mechanical Engineering |
| Organisation: |
UCL |
| Scheme: |
Standard Research |
| Starts: |
23 June 2008 |
Ends: |
22 December 2013 |
Value (£): |
1,517,247
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| EPSRC Research Topic Classifications: |
| Med.Instrument.Device& Equip. |
Medical Imaging |
| Medical science & disease |
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| EPSRC Industrial Sector Classifications: |
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| Related Grants: |
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| Panel History: |
| Panel Date | Panel Name | Outcome |
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09 Aug 2007
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HiFu Visiting Panel Meeting (ENG)
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Deferred
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21 Sep 2007
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Programme Grants Prioritisation Panel (Eng)
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Announced
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Summary on Grant Application Form |
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The efficacy of high intensity focused ultrasound (HIFU) for the non-invasive treatment of cancer has been clearly demonstrated for a range of different cancers including those of the liver, prostate and breast. As a non-invasive focal therapy, HIFU offers considerable advantages over other techniques such as chemotherapy and surgery, in terms of invasiveness and risk of harmful side-effects. Despite its advantages, however, there are a number of significant challenges currently hindering its widespread clinical application, specifically: the need to transmit energy through the rib cage and the associated risk of skin burns and damage to the rib surface, the effects of organ motion on treatment accuracy, a poor understanding of cavitation processes in vivo and, finally, the lack of effective techniques for real-time image guidance and treatment monitoring. The overall objective of the research programme described in this document is to develop practical solutions for these issues. Successful completion of this proposal will result in a prototype clinical device for the safe and effective HIFU treatment of tumours of the liver, kidney and pancreas that has undergone preclinical testing and conforms to the necessary safety standards for patient use.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
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