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Details of Grant 

EPSRC Reference: GR/J80672/01
Title: SELECTIVE ABSORPTION INVESTIGATION BY ELUENT GEL PERMEATION CHROMATOGRAPHY
Principal Investigator: Price, Professor C
Other Investigators:
Booth, Dr C Attwood, Professor D
Researcher Co-Investigators:
Project Partners:
Department: Chemistry
Organisation: Victoria University of Manchester, The
Scheme: Standard Research (Pre-FEC)
Starts: 01 October 1994 Ends: 30 September 1997 Value (£): 37,754
EPSRC Research Topic Classifications:
Materials Synthesis & Growth
EPSRC Industrial Sector Classifications:
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Summary on Grant Application Form
A new method of gel permeation chromatography (eluent GPC or EGPC) has been reported, and has potential in the study of micellar systems. A solution of an associating copolymer is used as a eluent, and a small volume of solvent (or solution of different concentration) is used to probe the association equilibrium in the eluent. Work is needed to establish the underlying mechanism, the methodology, and the range of application of the new technique. Investigation of multicomponent solutions which model systems of industrial and biomedical importance should be rewarding, since this would provide a rapid yet accurate probe of selective absorption. Interesting systems would be monomers solubilised in micelles, as in the early stages of emulsion polymerisation, and drugs solubilised in micelles for pharmaceutical use. The technique would have other important applications, e.g. in the investigation of the binding of counterions to polyelectrolytes.
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