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Details of Grant 

EPSRC Reference: GR/J92590/01
Title: TOTAL SYNTHESIS OF A83586C
Principal Investigator: Hale, Professor K
Other Investigators:
Researcher Co-Investigators:
Project Partners:
Department: Chemistry
Organisation: UCL
Scheme: Standard Research (Pre-FEC)
Starts: 01 October 1994 Ends: 30 September 1997 Value (£): 136,269
EPSRC Research Topic Classifications:
Biological & Medicinal Chem.
EPSRC Industrial Sector Classifications:
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Summary on Grant Application Form
1. To achieve the first total synthesis of antitumour antibiotic A83586C.2. To develop new methodology for constructing peptides containing a-hydrazino acid and b-hydroxy amino acid residues.3. To develop a new predictive model for the sharpless asymmetric dihydroxylation of 1,1-disubstituted olefins, and develop a new insight into its mechanism.
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