| EPSRC Reference: |
GR/K56360/01 |
| Title: |
MOLECULAR IMAGING IN DIAMOND (MIDIA) |
| Principal Investigator: |
Mainwood, Professor A |
| Other Investigators: |
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| Department: |
Physics |
| Organisation: |
Kings College London |
| Scheme: |
LINK |
| Starts: |
01 August 1995 |
Ends: |
31 December 1997 |
Value (£): |
73,107
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| EPSRC Research Topic Classifications: |
| Optical Devices & Subsystems |
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Summary on Grant Application Form |
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Nucleic acid bases and protein absorb UV light of shorter wavelength than 224nm very strongly, while other cell components such as lipids and carbohydrates are transparent in this region. This matches the spectral sensitivity of diamond. We propose to develop diamond detectors of a novel ridge design for use in nucleic acid sequencing and quantitation and tissue imaging. This will eliminate the hazardous radioactive or luminescent tags from many of these processes, with the associated handling and disposal problems. It will allow them to be completed in a few minutes or hours, rather than the days or weeks required at present, and will be a quantitative technique, easily digitised. The detectors will be fabricated from Chemical Vapour Deposition (CVD) diamond films with strips or pixel electrodes. They can detect UV lights and bs, which will allow the imaging of btagged drugs within tissue and UV absorption of the tissue itself to map the distribution of the drugs.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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