| EPSRC Reference: |
GR/M70230/01 |
| Title: |
INTEGRATING DETECTION AND PROCESSING INTO MINIATURISED CHROMATOGRAPHY SYSTEMS |
| Principal Investigator: |
Allinson, Professor NM |
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| Department: |
Electrical Engineering & Electronics |
| Organisation: |
UMIST |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
01 January 2000 |
Ends: |
31 December 2001 |
Value (£): |
54,087
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| No relevance to Underpinning Sectors |
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Summary on Grant Application Form |
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Though there is a high activity in microfabricated analytical systems, both in the UK and elsewhere, there is considerably less effort on the matching provision of effective illumination, detection and processing. This project aims to restore this imbalance. It exploits the existing synergy between experts in separation science, its instrumentation and advanced signal processing. Its broad objective is to integrate efficient micro-optical and detection systems, together with current digital processing techniques, with microfabricated wafer scale liquid chromatography and electrophoresis systems currently being developed by Professor Regnier (Purdue University, USA). In addition to providing direct visualisation of separations, our goal is to use the high linear dynamic range and spatial resolution of the detector to provide quantitative descriptions of all phases of separation and microanalytical processes. For example, using CCD imaging and feedback control of electrodrive voltage, reagent zones can be stopped precisely at the time of optimum overlap, then demixed at any time afterwards. The project tackles a number of the fundamental research themes identified in this EPSRC Programme - namely, enhanced information recovery and miniaturisation - yet remains tightly bound, through our industrial collaborators, with the needs of industry.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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